In the past Quercus alba was considered to be the source of the finest and most durable oak lumber in America for furniture and shipbuilding. Now it has been replaced almost entirely in commerce by various species of eastern red oak (e.g., Q . rubra , Q . velutina , and Q . falcata ) that are more common and have faster growth and greater yields. These red oaks also lack tyloses and therefore are more suited to pressure treating with preservatives, even though they are less decay-resistant without treatment.
Medicinally, Quercus alba was used by Native Americans to treat diarrhea, indigestion, chronic dysentery, mouth sores, chapped skin, asthma, milky urine, rheumatism, coughs, sore throat, consumption, bleeding piles, and muscle aches, as an antiseptic, and emetic, and a wash for chills and fevers, to bring up phlegm, as a witchcraft medicine, and as a psychological aid (D. E. Moerman 1986).
Numerous hybrids between Quercus alba and other species of white oak have been reported, and some have been named. J. W. Hardin (1975) reviewed the hybrids of Quercus alba . Nothospecies names based on putative hybrids involving Q . alba include: Q . × beadlei Trelease (= Q . alba × prinus ), Q . × bebbiana Schneider (= Q . alba × macrocarpa ), Q . × bimundorum E. J. Palmer (= Q . alba × robur ), Q . × deami Trelease (= Q . alba × muhlenbergii ), Q . × faxoni Trelease (= Q . alba × prinoides ), Q . × jackiana Schneider (= Q . alba × bicolor ), and Q . × saulei Schneider (= Q . alba × montana ).