Nodaviridae

This transmission electron micrograph (TEM) revealed the presence of numbers of Nodamura virus virions. At its core, the Nodamura virus possesses a positive-sense, single-stranded RNA virus ((+) ssRNA) genome. Its outer protein coat, or capsid, is icosahedral (T=3) in shape, which means that its composed of 32 equilateral, triangular facets.Created: 1975

This transmission electron micrograph (TEM) revealed the presence of numbers of Nodamura virus virions. At its core, the Nodamura virus possesses a positive-sense, single-stranded RNA virus ((+) ssRNA) genome. Its outer protein coat, or capsid, is icosahedral (T=3) in shape, which means that its composed of 32 equilateral, triangular facets.Created: 1975

This transmission electron micrograph (TEM) revealed the presence of numbers of Nodamura virus virions. At its core, the Nodamura virus possesses a positive-sense, single-stranded RNA virus ((+) ssRNA) genome. Its outer protein coat, or capsid, is icosahedral (T=3) in shape, which means that its composed of 32 equilateral, triangular facets.Created: 1975

Description: English: Crystal structure of GNNV, a betanodavirus. Date: 11 May 2016. Source: Own work. Author: Chunjungchen.

Description: English: Crystal structure of a betanodavirus, GNNV. Date: 11 May 2016. Source: Own work. Author: Chunjungchen.

Description: English: Crystal structure of a betanodavirus, GNNV. Date: 11 May 2016. Source: Own work. Author: Chunjungchen.

Description: English: X-ray diffraction of nodamura virus. Date: 14 January 1998. Source: "1NOV." RCSB PDB. N.p., n.d. Web. 10 Dec. 2015. Author: Natarajan, P., Johnson, J.E.

Description: English: Electron micrographs of negatively stained grouper nervous necrosis virus like particles used for crystallization. (A) T = 3 GNNV-LPs; (B) T = 1 SVPs of the N-ARM deletion mutant; (C) the delta-P-domain mutant. Bar: 100 nm. Date: 22 October 2015. Source: Chen N-C, Yoshimura M, Guan H-H, Wang T-Y, Misumi Y, Lin C-C, et al. (2015) Crystal Structures of a Piscine Betanodavirus: Mechanisms of Capsid Assembly and Viral Infection. PLoS Pathog 11(10): e1005203. https://doi.org/10.1371/journal.ppat.1005203. Author: Nai-Chi Chen, Masato Yoshimura, Hong-Hsiang Guan, Ting-Yu Wang, Yuko Misumi, Chien-Chih Lin, Phimonphan Chuankhayan, Atsushi Nakagawa, Sunney I. Chan, Tomitake Tsukihara, Tzong-Yueh Chen, Chun-Jung Chen. Other versions: .

Description: English: Nodamura virus coat protein trimer (3 beta and 3 gamma chain, blue). Date: 12 July 2016 (upload to Wikimedia Commons), 16 September 1997 (deposition at PDB). Source: http://www.rcsb.org/pdb/explore/explore.do?structureId=1nov. Author: Deposition authors: Natarajan, P., Johnson, J.E.; visualization author: User:Astrojan.

Description: English: Flock house virus genome organization and functional map of replicase protein A. (A) The bipartite FHV RNA genome encodes the viral replicase protein A on RNA1 and the capsid protein precursor on RNA2. Protein A mediates synthesis of a negative strand copy of the genomic RNAs which serves as template for synthesis of progeny positive strand RNAs, and an additional partial negative strand copy of RNA1 to template a 3’ co-terminal subgenomic RNA3. RNA3 potentially encodes protein B1, co-terminal with the C-terminus of protein A, and protein B2 which has anti-RNAi function. (B) A linear representation of protein A annotated to show membrane-association and enzymatic domains, and several regions independently capable of homotypic multimerization. Date: 27 June 2017. Source: eLife 2017;6:e25940 DOI: 10.7554/eLife.25940 https://elifesciences.org/articles/25940. Author: Kenneth J Ertel, Desirée Benefield, Daniel Castaño-Diez, Janice G Pennington, Mark Horswill, Johan A den Boon, Marisa S Otegui, and Paul Ahlquist. Other versions: .

Description: English: The overall structure of grouper nervous necrosis virus (GNNV). Surface domain-colored diagram (left) and central cavity (right) representations of the T = 3 GNNV-LP. The tip-to-tip distance is ~350 Å, the diameter of the central cavity is ~228 Å, and the spike protrusion on the capsid surface is ~47 Å. The S-domains of the subunits A, B and C are shown in orange, blue and red, respectively, and the P-domains are shown in cyan. The structure of the GNNV-LP is viewed along the I2, I3 and I5 axes. Date: 22 October 2015. Source: Chen N-C, Yoshimura M, Guan H-H, Wang T-Y, Misumi Y, Lin C-C, et al. (2015) Crystal Structures of a Piscine Betanodavirus: Mechanisms of Capsid Assembly and Viral Infection. PLoS Pathog 11(10): e1005203. https://doi.org/10.1371/journal.ppat.1005203. Author: Nai-Chi Chen, Masato Yoshimura, Hong-Hsiang Guan, Ting-Yu Wang, Yuko Misumi, Chien-Chih Lin, Phimonphan Chuankhayan, Atsushi Nakagawa, Sunney I. Chan, Tomitake Tsukihara, Tzong-Yueh Chen, Chun-Jung Chen. Other versions: .

Summary.mw-parser-output table.commons-file-information-table,.mw-parser-output.fileinfotpl-type-information{border:1px solid #a2a9b1;background-color:#f8f9fa;padding:5px;font-size:95%;border-spacing:2px;box-sizing:border-box;margin:0;width:100%}.mw-parser-output table.commons-file-information-table>tbody>tr,.mw-parser-output.fileinfotpl-type-information>tbody>tr{vertical-align:top}.mw-parser-output table.commons-file-information-table>tbody>tr>td,.mw-parser-output table.commons-file-information-table>tbody>tr>th,.mw-parser-output.fileinfotpl-type-information>tbody>tr>td,.mw-parser-output.fileinfotpl-type-information>tbody>tr>th{padding:4px}.mw-parser-output.fileinfo-paramfield{background:#ccf;text-align:right;padding-right:0.4em;width:15%;font-weight:bold}.mw-parser-output.commons-file-information-table+table.commons-file-information-table,.mw-parser-output.commons-file-information-table+div.commons-file-information-table>table{border-top:0;padding-top:0;margin-top:-8px}@media only screen and (max-width:719px){.mw-parser-output table.commons-file-information-table,.mw-parser-output.commons-file-information-table.fileinfotpl-type-information{border-spacing:0;padding:0;word-break:break-word;width:100%!important}.mw-parser-output.commons-file-information-table>tbody,.mw-parser-output.fileinfotpl-type-information>tbody{display:block}.mw-parser-output.commons-file-information-table>tbody>tr>td,.mw-parser-output.commons-file-information-table>tbody>tr>th,.mw-parser-output.fileinfotpl-type-information>tbody>tr>td,.mw-parser-output.fileinfotpl-type-information>tbody>tr>th{padding:0.2em 0.4em;text-align:left;text-align:start}.mw-parser-output.commons-file-information-table>tbody>tr,.mw-parser-output.fileinfotpl-type-information>tbody>tr{display:flex;flex-direction:column}.mw-parser-output.commons-file-information-table+table.commons-file-information-table,.mw-parser-output.commons-file-information-table+div.commons-file-information-table>table{margin-top:-1px}.mw-parser-output.fileinfo-paramfield{box-sizing:border-box;flex:1 0 100%;width:100%}} Description: Deutsch: Schemazeichnung eines Virions der Nodaviridae (Querscnitt und Seitenansicht). Date: 2008. Source: Modofied after https://viralzone.expasy.org/resources/Nodaviridae%5Fvirion.jpg at https://viralzone.expasy.org/47 For license see bottom right at https://viralzone.expasy.org. Modification: Genome is now shown as bipartit. Author: ViralZone, SIB Swiss Institute of Bioinformatics. Other versions: .

Description: English: Model of Flock house nodavirus (FHV) replication complex structure and function. (A) Amira-assisted 3D segmentation of a single virus replication compartment in FHV-infected cells. The spherule membrane (white) encloses the viral RNA (red) and is anchored to the mitochondrial outer membrane (dark blue), by the FHV protein A crown (light blue, derived from the subtomogram average). (B) Cartoon rendering of the image in (A). Viral RNA is shown as exiting the spherule to include the observation of fibrillary extrusions in many other tomograms. (C) Model of the FHV RNA complex and RNA synthesis, where positive-strand RNA (red) associates with protein A on the mitochondrial membrane to initiate the synthesis of negative-strand RNA (orange) and progeny positive-strand RNA accommodated by increasing volume of the spherule as if blowing up a balloon. In this model, subgenomic RNA3 results from attenuated negative strand synthesis and subse- quent positive-strand production in small spherules. Date: 27 June 2017. Source: eLife 2017;6:e25940 DOI: 10.7554/eLife.25940 https://elifesciences.org/articles/25940. Author: Kenneth J Ertel, Desirée Benefield, Daniel Castaño-Diez, Janice G Pennington, Mark Horswill, Johan A den Boon, Marisa S Otegui, and Paul Ahlquist.

Summary.mw-parser-output table.commons-file-information-table,.mw-parser-output.fileinfotpl-type-information{border:1px solid #a2a9b1;background-color:#f8f9fa;padding:5px;font-size:95%;border-spacing:2px;box-sizing:border-box;margin:0;width:100%}.mw-parser-output table.commons-file-information-table>tbody>tr,.mw-parser-output.fileinfotpl-type-information>tbody>tr{vertical-align:top}.mw-parser-output table.commons-file-information-table>tbody>tr>td,.mw-parser-output table.commons-file-information-table>tbody>tr>th,.mw-parser-output.fileinfotpl-type-information>tbody>tr>td,.mw-parser-output.fileinfotpl-type-information>tbody>tr>th{padding:4px}.mw-parser-output.fileinfo-paramfield{background:#ccf;text-align:right;padding-right:0.4em;width:15%;font-weight:bold}.mw-parser-output.commons-file-information-table+table.commons-file-information-table,.mw-parser-output.commons-file-information-table+div.commons-file-information-table>table{border-top:0;padding-top:0;margin-top:-8px}@media only screen and (max-width:719px){.mw-parser-output table.commons-file-information-table,.mw-parser-output.commons-file-information-table.fileinfotpl-type-information{border-spacing:0;padding:0;word-break:break-word;width:100%!important}.mw-parser-output.commons-file-information-table>tbody,.mw-parser-output.fileinfotpl-type-information>tbody{display:block}.mw-parser-output.commons-file-information-table>tbody>tr>td,.mw-parser-output.commons-file-information-table>tbody>tr>th,.mw-parser-output.fileinfotpl-type-information>tbody>tr>td,.mw-parser-output.fileinfotpl-type-information>tbody>tr>th{padding:0.2em 0.4em;text-align:left;text-align:start}.mw-parser-output.commons-file-information-table>tbody>tr,.mw-parser-output.fileinfotpl-type-information>tbody>tr{display:flex;flex-direction:column}.mw-parser-output.commons-file-information-table+table.commons-file-information-table,.mw-parser-output.commons-file-information-table+div.commons-file-information-table>table{margin-top:-1px}.mw-parser-output.fileinfo-paramfield{box-sizing:border-box;flex:1 0 100%;width:100%}} Description: Deutsch: Genomkarte der Nodaviridae. Date: (not specified). Source: Modified after https://viralzone.expasy.org/resources/Nodaviridae%5Fgenome.jpg at https://viralzone.expasy.org/47 For license see bottom right at https://viralzone.expasy.org - caption has been corrected (RNA-1 lentgh). Author: ViralZone, SIB Swiss Institute of Bioinformatics. Other versions: .