Streptomyces rimosus

Streptomyces rimosus is a bacterium species in the genus Streptomyces.

Uses

The antibiotics oxytetracycline and tetracycline are produced in cultures of S. rimosus. Paromomycin has also been isolated from cultures of S. rimosus.

Polyketide synthesis

S. rimosus's oxytetracycline polyketide synthase acyl carrier protein differs from most ACPs by having a C-terminus extension.^[1]

References

S. rimosus paromomycinus
S. rimosus rimosus

Streptomyces rimosus je bakterija iz rodu Streptomyces. Sodi med najbolj opisane industrijske streptomicete:^[1] znana je predvsem kot proizvajalka antibiotikov oksitetraciklin in tetraciklin, pa tudi protiglivne snovi rimocidin. Največ preiskav o vrsti so opravili raziskovalni inštitut za antibiotike v Moskvi, Pfizerjev osrednji raziskovalni laboratorij in Univerza v Glasgowu ter hrvaška Pliva, prvi podatki o mikromanipulaciji pa so iz 1957.^[2] Bakterija ima nitasto razrast in tvori substratni in zračni micelij.^[3]

Sklici

Viri

• Pigac, Jesenka; Hranueli, Daslav. "Optimal Cultural and Physiological Conditions for Handling Streptomyces rimosus Protoplasts". Applied and Environmental Microbiology (American Society for Microbiology) 44 (5): 1178–1186. Pridobljeno dne 6. maj 2014.
• Petković, Hrvoje; Cullum, John (2006). "Genetics of Streptomyces rimosus, the Oxytetracycline Producer". Microbiology and Molecular Biology Reviews (American Society for Microbiology) 70 (3): 704–728. Pridobljeno dne 6. maj 2014.
• Doskocil, J.; Sikyta, B. (1858). "Development of the Culture of Streptomyces rimosus in Submerged Fermentation" (PDF). Journal of general Microbiology 18: 302–314.