The Pseudonocardiaceae are a family of bacteria in the order Actinomycetales and the only member of the suborder Pseudonocardineae.
The species within the family Pseudonocardiaceae form a distinct clade in phylogenetic trees based on concatenated protein sequences. Additionally, Nakamurella multipartite, currently part of the order Frankiales, also formed a clade with the Pseudonocardiaceae species in 100% of the bootstrap replications of the phylogenetic trees. A conserved signature indel has been identified which is found in N. multipartite and all but one of the Pseudonocardiaceae species. This one-amino-acid insertion in UMP kinase serves to both provide a molecular marker for nearly all of the Pseudonocardiaceae and suggests N. multipartite is closely related to this group. Some evidence also suggests the orders Pseudonocardiales and Corynebacteriales are closely related. Several conserved signature indels have been identified which are found in both Pseudonocardiales and Corynebacteriales, including a three-amino-acid insertion in a conserved region of UDP-galactopyranose mutase. This insertion is also present in N. multipartite and Geodermatophilus obscurus, another member of Frankiales. Additionally, five conserved signature proteins have been identified which are found only in the orders Pseudonocardiales and Corynebacterialess. Homologs of the proteins are generally found in N. multipartite and G. obscurus, providing additional evidence of these two species being closely related to the orders Pseudonocardiales and Corynebacteriales.[3]
Pseudonocardiaceae comprises the following genera:[4]
The currently accepted taxonomy is based on the List of Prokaryotic names with Standing in Nomenclature (LPSN).[4] The phylogeny is based on whole-genome analysis.[5][a]
Pseudonocardiales outgroupThe Pseudonocardiaceae are a family of bacteria in the order Actinomycetales and the only member of the suborder Pseudonocardineae.
