Silene jenisseensis, is a species of flowering plant in the family Caryophyllaceae, native to Siberia, Far East and Mongolia.[1]
Chemistry
Phytochemical analysis of Silene jenisseensis roots have found ecdysteroid 20-hydroxyecdysone, sterol α-spinasterol-3-O-glucoside,[2] triterpenoids quillaic acid derivatives — jenisseensoside A, B, C and D.[3][4][5] In herb of Silene jenisseensis flavone-C-glycosides were detected including vitexin, isovitexin, orientin, isoorientin,[6] as well as ecdysteroids 2-desoxyecdysone, 2-desoxy-20-hydroxyecdysone, ponasterone A, dacryhainansterone, 20-hydroxyecdysone and integristerone A.[7] Total content of ecdysteroids in Silene jenisseensis roots and herb collected in Buryatia Republic was 0.06% and 0.06—0.83%, respectively.
Uses
Triterpenoids jenisseensoside A—D showed inhibitory effect in the cyclooxygenase inhibition assay,[3] significant enhancement of the granulocyte phagocytosis,[4] and cytotoxicity against human colon cancer cells (HP 29).[5]
References
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^ Flora Sibiri : [v 14 tomach]. T. 6 Portulacaceae - Ranunculaceae. Central'nyj Sibirskij Botaničeskij Sad Nowosibirsk. Novosibirsk: Izd."Nauka", Sibirskoe otdnie. 1993. ISBN 5020301329. OCLC 832920941.
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^ Cui, Z.-H.; Qiao, L.; Gao, C.-Y.; Lou, Z.-C. (1995). "Chemical constituents of Silene jenisseensis". Journal of Chinese Pharmaceutical Sciences. 4: 30–31.
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^ a b Lacaille-Dubois, Marie-Aleth; Hanquet, Bernard; Cui, Zhen-Hua; Lou, Zhi-Cen; Wagner, Hildebert (September 1995). "Acylated triterpene saponins from Silene jenisseensis". Phytochemistry. 40 (2): 509–514. doi:10.1016/0031-9422(95)00222-S. PMID 7546560.
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^ a b Lacaille-DuBois, Marie-Aleth; Hanquet, Bernard; Cui, Zhen-Hua; Lou, Zhi-Cen; Wagner, Hildebert (July 1997). "Jenisseensosides C and D, biologically active acylated triterpene saponins from Silene jenisseensis". Phytochemistry. 45 (5): 985–990. doi:10.1016/S0031-9422(97)00087-3. PMID 9264608.
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^ a b Gaidi, Ghezala; Correia, Maria; Chauffert, Bruno; Beltramo, Jean-Luc; Wagner, Hildebert; Lacaille-Dubois, Marie-Aleth (January 2002). "Saponins-Mediated Potentiation of Cisplatin Accumulation and Cytotoxicity in Human Colon Cancer Cells". Planta Medica. 68 (1): 70–72. doi:10.1055/s-2002-19873. PMID 11842333.
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^ Darmograi V.N. (1977). "Flavonoids of plants of the genera Silene and Otites Adans, family Caryophyllaceae". Chemistry of Natural Compounds. 33: 102–103. doi:10.1007/BF00566187. S2CID 10588205.
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^ Olennikov, D. N.; Kashchenko, N. I. (November 2017). "Phytoecdysteroids from Silene jenisseensis". Chemistry of Natural Compounds. 53 (6): 1199–1201. doi:10.1007/s10600-017-2239-1. ISSN 0009-3130. S2CID 102676932.
