Die Betaherpesvirinae bilden eine Unterfamilie der Virusfamilie Herpesviridae. Sie besteht aus folgenden Gattungen (mit wichtigsten Virusspezies):
Die Betaherpesvirinae bilden eine Unterfamilie der Virusfamilie Herpesviridae. Sie besteht aus folgenden Gattungen (mit wichtigsten Virusspezies):
Genus Cytomegalovirus Spezies Humanes Herpesvirus 5 (HHV-5) = Humanes Cytomegalievirus (HCMV) (Typus) Spezies Pongines Herpesvirus 4 (PoHV-4) = Schimpansen-Cytomegalievirus Spezies Makaken-Herpesvirus 3 = Rhesus-Cytomegalovirus (RhCMV) Genus Muromegalovirus (bei Muridae) Spezies Murides Herpesvirus 1 (MuHV-1) = Murines Cytomegalievirus (MCMV) (Typus) Spezies Murides Herpesvirus 2 (MuHV-2) = Ratten-Cytomegalievirus (RCMV) Maastricht Spezies Murides Herpesvirus 8 (MuHV-8) = Ratten-Cytomegalievirus (RCMV) England/Berlin Genus Roseolovirus Spezies Humanes Herpesvirus 6A (HHV-6A, Typus) Spezies Humanes Herpesvirus 6B (HHV-6B) Spezies Humanes Herpesvirus 7 (HHV-7) Genus Proboscivirus Spezies Elephantid betaherpesvirus 1 (Typus) Spezies Elephantid betaherpesvirus 1 Spezies Elephantid betaherpesvirus 1 nicht klassifizierte Spezies innerhalb der Unterfamilie Betaherpesvirinae: Spezies Meerschweinchen-Herpesvirus 2 (CavHV-2) Spezies Tupaia-Herpesvirus 1 (TuHV-1) Spezies Suides Herpesvirus 2Betaherpesvirinae nyaéta subfamili Herpesviridae nu bisa dibedakeun ku cara réproduksi nu leuwih laun ti batan subfamili Herpesviridae liana.
Grup Studi Herpesviridae geu ngusulkeun yén subfamily Betaherpesvirinae dibagi jadi opat genera:[1]
Betaherpesvirinae nyaéta subfamili Herpesviridae nu bisa dibedakeun ku cara réproduksi nu leuwih laun ti batan subfamili Herpesviridae liana.
Grup Studi Herpesviridae geu ngusulkeun yén subfamily Betaherpesvirinae dibagi jadi opat genera:
Cytomegalovirus Muromegalovirus Roseolovirus Proboscivirus
Betaherpesvirinae is a subfamily of viruses in the order Herpesvirales and in the family Herpesviridae. Mammals serve as natural hosts. There are 26 species in this subfamily, divided among 5 genera. Diseases associated with this subfamily include: human cytomegalovirus (HHV-5): congenital CMV infection; HHV-6: 'sixth disease' (also known as roseola infantum or exanthem subitum); HHV-7: symptoms analogous to the 'sixth disease'.[1][2]
Betaherpesvirinae consists of the following five genera:[2]
Viruses in Betaherpesvirinae are enveloped, with icosahedral, spherical to pleomorphic, and Round geometries, and T=16 symmetry. The diameter is around 150-200 nm. Genomes are linear and non-segmented, around 140-240kb in length.[1]
Viral replication is nuclear, and is lysogenic. Entry into the host cell is achieved by attachment of the viral glycoproteins to host receptors, which mediates endocytosis. Replication follows the dsDNA bidirectional replication model. DNA templated transcription, with some alternative splicing mechanism is the method of transcription. Translation takes place by leaky scanning. The virus exits the host cell by nuclear egress and budding. Betaherpesviruses typically have highly restricted host ranges, although essentially all mammals, reptiles, and birds are infected with at least one betaherpesvirus species. Transmission routes are transplacental, transplantation, blood transfusion, body fluids, urine, and saliva.[1]
Betaherpesvirinae establish latency (site where virus lies dormant until reactivated) in CD34+ myeloid progenitor cells and CD14+ monocytes.[3] This is different from Alphaherpesvirinae, which establish latency in neurons, and Gammaherpesvirinae, which establish latency in memory B cells.[3]
There are four known member species of the Betaherpesvirinae subfamily that are infectious for humans:
Human cytomegalovirus (HCMV, HHV-5) "seems to have a large impact on immune parameters in later life and may contribute to increased morbidity and eventual mortality."[5] Human herpesvirus 6A (HHV-6A) has been described as more neurovirulent,[6] and as such is more frequently found in patients with neuroinflammatory diseases such as multiple sclerosis.[7] Both human herpesvirus 6B (HHV-6B) and human herpesvirus 7 (HHV-7), as well as other viruses, can cause a skin condition in infants known as exanthema subitum, roseola infantum (rose rash of infants) or the sixth disease.
Betaherpesvirinae is a subfamily of viruses in the order Herpesvirales and in the family Herpesviridae. Mammals serve as natural hosts. There are 26 species in this subfamily, divided among 5 genera. Diseases associated with this subfamily include: human cytomegalovirus (HHV-5): congenital CMV infection; HHV-6: 'sixth disease' (also known as roseola infantum or exanthem subitum); HHV-7: symptoms analogous to the 'sixth disease'.
Los Betaherpesvirinae son una subfamilia de virus ADN de vertebrados de la familia Herpesviridae, de crecimiento lento, con genoma de ADN grande, causan citomegalia con la peculiaridad de vivir en latencia den las glándulas salivales, riñones, macrófagos y linfocitos del hospedador, el cual por lo general son especies específicos.[1] Entre las especies de betaherpesvirinae se encuentran patógenos animales:
Los Betaherpesvirinae son una subfamilia de virus ADN de vertebrados de la familia Herpesviridae, de crecimiento lento, con genoma de ADN grande, causan citomegalia con la peculiaridad de vivir en latencia den las glándulas salivales, riñones, macrófagos y linfocitos del hospedador, el cual por lo general son especies específicos. Entre las especies de betaherpesvirinae se encuentran patógenos animales:
Cricetid Herpesvirus 1 Herpesvirus Humano (beta) 5 (Citomegalovirus) Herpesvirus Humano 6 (Roseolovirus o roseola) Herpesvirus Humano 7 Herpesvirus Murino 1 Herpesvirus Porcino 2Betaherpesvirinae è una sottofamiglia della famiglia Herpesviridae, principalmente contraddistinta per il proprio tasso di riproduzione più lento, in comparazione alle altre sottofamiglie di Herpesviridae.
I generi appartenenti a questa sottofamiglia sono i seguenti:[1]
Alla sottofamiglia vanno aggiunte anche le specie Caviid betaherpesvirus 2 e Tupaiid betaherpesvirus 1, non assegnate ad alcun genere.
Il loro sito di latenza (le cellule in cui si annidano dopo la prima infezione) è costituito dai leucociti, dalle ghiandole salivari, dai tubuli renali.
Betaherpesvirinae è una sottofamiglia della famiglia Herpesviridae, principalmente contraddistinta per il proprio tasso di riproduzione più lento, in comparazione alle altre sottofamiglie di Herpesviridae.
I generi appartenenti a questa sottofamiglia sono i seguenti:
Cytomegalovirus Muromegalovirus Roseolovirus Herpesvirus umano 6 e Herpesvirus umano 7 ProboscivirusAlla sottofamiglia vanno aggiunte anche le specie Caviid betaherpesvirus 2 e Tupaiid betaherpesvirus 1, non assegnate ad alcun genere.
Il loro sito di latenza (le cellule in cui si annidano dopo la prima infezione) è costituito dai leucociti, dalle ghiandole salivari, dai tubuli renali.
De subfamilie betaherpesvirinae behoort tot de familie herpesviridae. Deze virussen besmetten enkel zoogdieren. Momenteel zijn er 18 geslachten bekend binnen deze subfamilie.
Virussen in de Betaherpesvirinae-subfamilie hebben een celenvelop, zijn sferisch pleomorfisch en hebben ronde geometrieën (T = 16). Hun diameter ligt tussen de 150 en 200 nm. Hun genomen zijn lineair en niet-gesegmenteerd, tussen de 140 en 240 kilobases in lengte.
Dit virus is lysogenisch: het nestelt zich in de gastheercel zonder direct voor de dood van de cel te zorgen.
Ingang in de gastheercel gebeurt door contact van het viraal erfelijk materiaal met de receptoreiwitten van de gastheercel, waarna endocytose aan de gang komt. Het virale erfelijk materiaal zal zich vermenigvuldigen en er worden nieuwe virussen gevormd. De virussen blijven echter in de gastheercel totdat ze kunnen uitbreken (als het immuunsysteem bijvoorbeeld verzwakt is).
De subfamilie betaherpesvirinae behoort tot de familie herpesviridae. Deze virussen besmetten enkel zoogdieren. Momenteel zijn er 18 geslachten bekend binnen deze subfamilie.
Betaherpesvirinae
Группа по БалтиморуI: дцДНК-вирусы
Бетагерпесвирусы[2] или β-герпесвирусы (лат. Betaherpesvirinae) — подсемейство вирусов, входящее в семейство герпесвирусов.
Бетагерпесвирусы имеют длительный цикл репликации, могут находиться в латентном состоянии в разных органах и тканях (лейкоцитах, железах секреции, почках и т. д.)
Они имеют ограниченный диапазон носителей и отличаются медленным ростом в культуре.
По данным Международного комитета по таксономии вирусов (ICTV), на май 2016 г. в подсемейство включают следующие роды[3]:
Бетагерпесвирусы или β-герпесвирусы (лат. Betaherpesvirinae) — подсемейство вирусов, входящее в семейство герпесвирусов.
Бетагерпесвирусы имеют длительный цикл репликации, могут находиться в латентном состоянии в разных органах и тканях (лейкоцитах, железах секреции, почках и т. д.)
Они имеют ограниченный диапазон носителей и отличаются медленным ростом в культуре.
ベータヘルペスウイルス亜科(ベータヘルペスウイルスあか、Betaherpesvirinae)とは、ヘルペスウイルス科の亜科。
以下の属がある。
ベータヘルペスウイルス亜科(ベータヘルペスウイルスあか、Betaherpesvirinae)とは、ヘルペスウイルス科の亜科。
以下の属がある。
サイトメガロウイルス ムロメガロウイルス ロゼオロウイルス プロバシスウイルス