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Faecalibacterium is a genus of bacteria. Its sole known species, Faecalibacterium prausnitzii is Gram-positive,[1] mesophilic, rod-shaped,[2] and anaerobic,[3] and is one of the most abundant and important commensal bacteria of the human gut microbiota. It is non-spore forming and non-motile.[4] These bacteria produce butyrate and other short-chain fatty acids through the fermentation of dietary fiber.
Formerly considered to be a member of Fusobacterium, the bacterium is named in honor of German bacteriologist Otto Prausnitz. In 2002, it was proposed to be reclassified as its own genus, Faecalibacterium, containing the species Faecalibacterium prausnitzii, as phylogenetic analysis from isolates showed it to be only distantly related to Fusobacterium, and a closer member of Clostridium cluster IV.[5]
Faecalibacterium prausnitzii has a genome 2,868,932 bp long and has a GC-content of 56.9%. The bacterium has been found to have 2,707 coding sequences, including 77 RNAs encoding genes.[6] 128 metabolic pathways have been reconstructed, as well as 27 protein complexes and 64 tRNAs.[7] Phylogenetically, the strains of F. prausnitzii compose phylogroups I and II. Most of the new isolates of this species isolated by Muhammad Tanweer Khan belong to phylogroup II.[8] A protein produced by this bacterium has been linked to anti-inflammatory effects.[9]
In healthy adults, Faecalibacterium prausnitzii represent more than 5% of the bacteria in the intestine, making it one of the most common gut bacteria. It has anti-inflammatory properties and may improve the imbalance in intestinal bacteria that leads to dysbiosis.[10] Lower than usual levels of F. prausnitzii in the intestines have been associated with Crohn's disease, obesity, asthma and major depressive disorder,[11][12][13][14] and higher than usual levels have been associated with psoriasis.[15] Faecalibacterium prausnitzii can improve gut barrier function.[16]
In Crohn's disease, as of 2015 most studies (with one exception) found reduced levels of F. prausnitzii;[17] this has been found in both fecal and mucosal samples.[18] However, it is a fastidious organism sensitive to oxygen and difficult to deliver to the intestine.[18]
Exclusive enteral nutrition, which is known to induce remission in Crohn's, has been found to reduce F. prausnitzii in responders.[19]
Faecalibacterium is a genus of bacteria. Its sole known species, Faecalibacterium prausnitzii is Gram-positive, mesophilic, rod-shaped, and anaerobic, and is one of the most abundant and important commensal bacteria of the human gut microbiota. It is non-spore forming and non-motile. These bacteria produce butyrate and other short-chain fatty acids through the fermentation of dietary fiber.
Faecalibacterium es un género de bacterias. Su única especie conocida, Faecalibacterium prausnitzii es un gram positivo,[1] mesofílica, con forma de bastónd,[2] anaeróbica[3] y es una de las bacterias comensales más abundantes de la microbiota humana. Otra de sus características es la incapacidad de moverse ni generar esporas.[4] Dentro de los compuestos producidos por esta bacteria destacan el butirato así como también otros ácidos grasos de cadena corta a través de la fermentación de la fibra dietética.
En los individuos sanos, Faecalibacterium prausnitzii representa más del 5% de las bacterias del intestino, haciéndola una de las más prevalentes. Se ha asociado con un efecto potenciador del sistema inmune.[5] Niveles bajos de dicha bacteria se han asociado con algunas enfermedades como Enfermedad de Crohn, obesidad, asma y episodio depresivo mayor,[6][7][8][9] mientras que niveles muy elevados se han asociado a Psoriasis.[10]
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Datos: Q3738294
Especies: Faecalibacterium
Faecalibacterium es un género de bacterias. Su única especie conocida, Faecalibacterium prausnitzii es un gram positivo, mesofílica, con forma de bastónd, anaeróbica y es una de las bacterias comensales más abundantes de la microbiota humana. Otra de sus características es la incapacidad de moverse ni generar esporas. Dentro de los compuestos producidos por esta bacteria destacan el butirato así como también otros ácidos grasos de cadena corta a través de la fermentación de la fibra dietética.
Faecalibacterium est un genre de bactéries, dont la seule espèce connue, Faecalibacterium prausnitzii, est gram-positive[2], anaérobie, et une des plus abondantes dans le microbiote humain. Elle est non mobile[3].
Elle produit des acides gras à courte chaîne qui ont des effets anti-inflammatoires lors de la fermentation des fibres pendant la digestion[4].
Son absence dans l'intestin jouerait un rôle dans certaines maladies, comme la maladie de Crohn[5] ou le syndrome de l'intestin irritable.
Faecalibacterium est un genre de bactéries, dont la seule espèce connue, Faecalibacterium prausnitzii, est gram-positive, anaérobie, et une des plus abondantes dans le microbiote humain. Elle est non mobile.
Elle produit des acides gras à courte chaîne qui ont des effets anti-inflammatoires lors de la fermentation des fibres pendant la digestion.
Son absence dans l'intestin jouerait un rôle dans certaines maladies, comme la maladie de Crohn ou le syndrome de l'intestin irritable.
Faecalibacterium è un genere di batterio appartenente alla famiglia delle Clostridiaceae.
Faecalibacterium è un genere di batterio appartenente alla famiglia delle Clostridiaceae.
Faecalibacterium é um género de bactéria. Sua única espécie conhecida, Faecalibacterium prausnitzii, é uma importante bactéria comensal da flora intestinal humana[1]. Existem evidências da eficácia de Faecalibacterium na prevenção do desenvolvimento de asma[2].
Faecalibacterium é um género de bactéria. Sua única espécie conhecida, Faecalibacterium prausnitzii, é uma importante bactéria comensal da flora intestinal humana. Existem evidências da eficácia de Faecalibacterium na prevenção do desenvolvimento de asma.
