Endemic to the Gulf of California. There are erroneous reports in the literature that that this species occurs outside the Gulf of California along the Pacific Coast of Mexico and Central America (e.g. Caso, 1977: The echinoids of the Pacific coast of Mexico, third part - order Clypeasteroida; Neira & Cantera, 2005: Taxonomic composition and distribution of the echinoderms associations in the littoral ecosystems from the Colombian Pacific; Alvarado, Solis-Marin & Ahearn, 2010: Echinoderm diversity in the Pacific coast of Central America). These reports appear to be based on misidentifications or mistakes in the cataloguing of specimens.
Encope grandis is een zee-egel uit de familie Mellitidae.
De wetenschappelijke naam van de soort werd in 1841 gepubliceerd door Louis Agassiz.
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