Journal.ppat.1000147.g001

Description :

Description: English: The MC179 structure and PfEMP1. (A) Two CIDR and four DBL domains compose the extracellular portion. (B) The MC179 structure is made up of three helices (H1, dark blue; H2, light blue; H3, red) that form a three-helix bundle and three additional helices (a, b, c; yellow) that connect H2 to H3. (C) View of MC179 after reorienting by 90°. (D) MC179 topology diagram shows how the six helices are connected. Date: 5 September 2008. Source: The Cysteine-Rich Interdomain Region from the Highly Variable Plasmodium falciparum Erythrocyte Membrane Protein-1 Exhibits a Conserved Structure. https://dx.doi.org/10.1371/journal.ppat.1000147. Author: Michael M. Klein, Apostolos G. Gittis, Hua-Poo Su, Morris O. Makobongo, Jaime M. Moore, Sanjay Singh, Louis H. Miller, David N. Garboczi.