DOI 10.5772 55289 image1 w

Kuvaus:

Description: English: Genomes of influenza viruses. A) The ends of the negative strand influenza genomic RNA are complexed with the three polymerase proteins and the remaining sequence is encapsidated with nucleoprotein (vRNP (-)). The positive strand cRNP is similarly complexed. The mRNA is transcribed with a 5’ cap structure and poly-A tail (see main text for details). Figure used with permission from Resa-Infante et al., 2011. B) Schematic of the influenza A virus genome. The bold black lines represent the 3’ and 5’ untranslated regions. The blue and pink boxes represent the major protein coding regions. C) Schematic of the influenza B virus genome. The green and brown boxes represent the major protein coding regions. D) Schematic of the influenza C virus genome. The red and purple boxes represent the major protein coding regions. The protein coding regions are not to scale. Coding regions in a different reading frame are shown above or below each other, coding regions in the same frame are show as contiguous blocks. Date: 20 November 2013. Source: https://www.intechopen.com/books/current-issues-in-molecular-virology-viral-genetics-and-biotechnological-applications/gene-constellation-of-influenza-vaccine-seed-viruses. Author: Ewan P. Plant and Zhiping Ye.